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Displaying results 2651 - 2660 of 10000 in total
  1. Drug

    Vilastobart

    go.drugbank.com/drugs/DB19327
    Investigational

    Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).

    Synonyms: G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-, gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14,
  2. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. … Two years later, the research group isolated a compound structurally similar to hydroxymethylglutarate (HMG) that inhibited the incorporation of acetate.

  3. Indication

    Influenza caused by pandemic (H1N1) 2009 virus

    go.drugbank.com/conditions/DBCOND0093734
    Drugs: Influenza A virus A/California/7/2009(H1N1)-like antigen (formaldehyde inactivated)
    Synonyms: Influenza caused by pandemic (H1N1) 2009 virus
  4. Drug

    Nicoboxil

    go.drugbank.com/drugs/DB12911
    ApprovedWithdrawn

    Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option. … Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately synergistic

    Mixtures: Nonivamid + Nicoboxil Zentiva 4 mg/g + 25 mg/g Salbe
  5. Drug

    Thiothixene

    go.drugbank.com/drugs/DB01623
    Approved

    A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

    Products: Navane Cap 2mg
  6. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    In 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers. … It is used as an appetite suppressant and a treatment for obesity.

    International brands: Desobesi-M
  7. Drug

    XT-150

    go.drugbank.com/drugs/DB21756
    Investigational

    XT-150 is a locally injectable non-viral therapy expressing IL-10v, a proprietary modified variant of IL-10.[L52125] It is being developed by Xalud Therapeutics.

    Synonyms: non-viral human interleukin-10 (IL-10) variant (IL-10var) encoding plasmid deoxyribonucleic acid (pDNA)
  8. Drug

    Chlorobutanol

    go.drugbank.com/drugs/DB11386
    ApprovedVet approvedWithdrawn

    As a long-term stabilizer of multi-ingredient preparations, chlorobutanol is normally used at a concentration of 0.5%. At this concentration, it also conserves its antimicrobial activity. … Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone.

    Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, NOSTIL 75 MG/60MG/35MG BURUN SPREYİ, ÇÖZELTİ, 15 ML
  9. Drug

    AMG 108

    go.drugbank.com/drugs/DB05545
    Investigational

    AMG 108 was investigated for use as an antirheumatic agent.

  10. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. … It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease.

    Mixtures: EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75 g/l, EXTRANEFROL PERİTON DİYALİZ ÇÖZELTİSİ, 2000 ML TEKLİ