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Urapidil
go.drugbank.com/drugs/DB12661InvestigationalUrapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingProducts: UPADİL 25 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, PİDİLAX 25 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADETDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigationalDrospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol]. … Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events.
Mixtures: LÍA, Lo-ZumandimineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationalMidazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. … [A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.[L5074]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: N/a, Epistatus 5 mg Lösung zur Anwendung in der MundhöhleSO-101
go.drugbank.com/drugs/DB05345ExperimentalSO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. … Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
Quinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Mixtures: QUINAPRIL E IDROCLOROTIAZIDE ACTAVIS, QUINAPLUS AL 20MG/25MGCategories: Heterocyclic Compounds, 2-RingEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedAs a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in … Estradiol acetate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: Estradiol 3-acetate, Estradiol-3-acetatePost-essential Thrombocythemia Myelofibrosis (Post-ET MF)
go.drugbank.com/conditions/DBCOND0069581Drugs: RuxolitinibSynonyms: Thrombocythemia Myelofibrosis (PET-MF), Post-essential Thrombocythemia Myelofibrosis (PET-MF)Yohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsInternational brands: Baron-XSodium sulfate
go.drugbank.com/drugs/DB09472ApprovedInvestigationalVet approvedSodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances.
Mixtures: PEG-3350 and Electrolytes, PEG-3350 and ElectrolytesSegesterone acetate
go.drugbank.com/drugs/DB14583ApprovedSegesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 [A37048]. … In clinical trials, Annovera™ achieved a 97.3% success in pregnancy prevention [L4246]. Annovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each cycle.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione, 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate