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Talmapimod
go.drugbank.com/drugs/DB05412InvestigationalIt has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.
Interferon Gamma
go.drugbank.com/drugs/DB15753InvestigationalIt has antitumor properties, antiviral activities, and important immunoregulatory functions. The interferon is primarily produced by activated T lymphocytes and natural killer cells.
Cerulenin
go.drugbank.com/drugs/DB01034ExperimentalCerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol sy...
Durlobactam
go.drugbank.com/drugs/DB16704ApprovedInvestigational[L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023.
Gluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalCommonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Cabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigational[A227668,L31193] Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 infection in virologically suppressed individuals. … [L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in
Tocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigational[L43697] After being investigated to treat severely ill patients with COVID-19,[A193278,L12837,L12843] tocilizumab was approved by the European Commission in December 2021 to treat COVID-19 in adults receiving … [L12789] It was later approved by Health Canada on 30 April 2010.
Trastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalThe FDA label has two precautions. First that trastuzumab emtansine and trastuzumab cannot be interchanged. … Second that there is a black box warning of serious side effects such as hepatotoxicity, embryo-fetal toxicity, and cardiac toxicity.
Afamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]
Piperacetazine
go.drugbank.com/drugs/DB06808ApprovedVet approvedWithdrawnPiperacetazine was an antipsychotic.