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Lutein
go.drugbank.com/drugs/DB00137ApprovedNutraceuticalLutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. … In green plants, xanthophylls act to modulate light energy and serve as non-photochemical quenching agents to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very
Hydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalneed for therapeutic monitoring, and serious side effects of secondary cancer and birth defects. … Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Categories: Antineoplastic and Immunomodulating AgentsLutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalPatients with GEP-NETs have limited second-line treatment options after the metastasis of tumors and inadequate therapeutic response from first-line therapies. … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with
Categories: Indicators and Reagents, Somatostatin and AnaloguesTocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalTocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E. … When the carbons at position 5- and 7- are not methylated, they can function as electrophilic centers that can trap reactive oxygen and nitrogen species.
Mixtures: MultiVitamin Drops with Fluoride and IronCategories: Alimentary Tract and Metabolism, Diet, Food, and NutritionAlclofenac
go.drugbank.com/drugs/DB13167ApprovedWithdrawnIt was withdrawn from the market in the United Kingdom in 1979.
Categories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsAcetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978. … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it is the first monomeric ionic compound used as an X-ray contrast agent.
Defibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalIt has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects). … Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA.
Categories: Blood and Blood Forming Organs, Nucleic Acids, Nucleotides, and NucleosidesGeraniol
go.drugbank.com/drugs/DB14183ApprovedIt is emitted from the flowers of many species of plant and is commonly used by the food, fragrance, and cosmetic industry[L3333]. … These pharmacologic effects are clinically important as geraniol is classified as generally-recognized-as-safe (GRAS) by the Flavor and Extract Manufacturers Association (FEMA) and the Food and Drug Administration
Measles virus vaccine live attenuated
go.drugbank.com/drugs/DB10315ApprovedInvestigationalThe vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.
Mixtures: MEASLES AND RUBELLA VIRUS VACCINE LIVE, SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 doseReserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnIt has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use. … Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals.
Categories: reserpine and diuretics, reserpine and diuretics, combinations with other drugs