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3-oxoacyl-[acyl-carrier-protein] synthase 1
go.drugbank.com/bio_entities/BE0000801TargetEscherichia coli (strain K12)Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor (PubMed:19679654, PubMed:22017312, PubMed:8910376, PubMed:90138...
Synonyms: KAS IC326
go.drugbank.com/drugs/DB06017ExperimentalThe drug is composed of an IL-6–binding trimer and a IgG-binding domain. … C326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment
Seproxetine
go.drugbank.com/drugs/DB06731ExperimentalSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. … Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: (S)-norfluoxetineSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnSibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. … It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: TALLARME®, OBESTOP® 10 MG CAPSULASSarracenia Purpurea
go.drugbank.com/drugs/DB13965ApprovedWithdrawnIt was used as an injectable pain reliever and during the 19th century, _Sarracenia purpurea_ was used as a treatment of smallpox [A32509]. … It is widely distributed across North America and has been used as a traditional medicinal herb in many aboriginal communities [A32509, A32510].
Synonyms: Sarracenia purpurea l.Products: P-BlocDimercaprol
go.drugbank.com/drugs/DB06782ApprovedDimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. … It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning.
Categories: Compounds used in a research, industrial, or household settingSynonyms: α,β-dithioglycerol, 1,2-dimercapto-3-propanolTriptorelin
go.drugbank.com/drugs/DB06825ApprovedInvestigationalVet approvedSerum testosterone concentrations may fall to levels typically observed in surgically castrated men. … Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH).
Synonyms: pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2, (6-D-Tryptophan)luteinizing hormone-releasing hormoneProducts: DECAPEPTYL® 11.25MG, DECAPEPTYL 0,5 MG/ML ENJEKTABL SOLÜSYON, 7 ADETBird pepper
go.drugbank.com/drugs/DB14262ApprovedBird pepper is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Rice bran
go.drugbank.com/drugs/DB14361ApprovedRice bran is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Ari S-LinerHuman Menstrual Blood-derived Stem Cells
go.drugbank.com/drugs/DB15738InvestigationalBecause this is a non-invasive way to obtain stem cells, it is simple and easy to obtain the stem cells with an absence of ethical issues that may come from obtaining stem cells of the embryonic kind. … These cells possess a high rate of proliferation and multi-lineage differentiation potency.