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Displaying results 261 - 270 of 10000 in total
  1. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.

    Mixtures: Magnesium Sulfate In 5% Dextrose Inj(20mg/ml), Vamin NSynonyms: magnesium(II) sulfate, Magnesium sulfate (1:1)
  2. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    NPH insulin is provided as a crystalline suspension of insulin with protamine and zinc, resulting in an onset of action in 1 to 3 hours, duration of action up to 24 hours, and peak action from 6 to 8 hours … Human insulin is also available in an inhalable form, intended to be used as a bolus meal-time insulin.

    Mixtures: INSUMAN COMB 25 100I E/ML, INSUMAN COMB 25 100I E/MLCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 Inducers
  3. Pathway

    Indium In-111 oxyquinoline Drug Metabolism

    smpdb.ca/view/SMP0130676
    Metabolic

    Indium In-111 oxyquinoline passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 oxyquinoline is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Indium In-111 oxyquinoline
  4. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. … It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).

    Products: BENEPALI 50MG ILO I E FER, Enbrel Solution for Injection in a Pre-filled Pen 50mg
  5. Pathway

    Fatty Acid Elongation in Mitochondria

    smpdb.ca/view/SMP0000054
    Metabolic

    In liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required. … Mitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation.

    Drugs: NADH · Palmitic Acid
  6. Pathway

    Indium In-111 pentetate Drug Metabolism

    smpdb.ca/view/SMP0130595
    Metabolic

    Indium In-111 pentetate passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 pentetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Indium In-111 pentetate
  7. Drug

    Rabies immune globulin, human

    go.drugbank.com/drugs/DB11603
    Approved

    IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced … IMOGAM Rabies Pasteurized should be administered promptly after exposure, in conjunction with rabies vaccine.

    Products: EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET, Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze
  8. Target

    Apolipoprotein E

    go.drugbank.com/bio_entities/BE0001119
    TargetCarrierHumans

    First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues (PubMed:14754908, PubMed:23620513). … APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting (PubMed:25173806, PubMed:8939961).

    Polypeptides: Apolipoprotein ESynonyms: Apo-E
  9. Target

    Carboxypeptidase E

    go.drugbank.com/bio_entities/BE0001123
    EnzymeTargetHumans

    Also acts as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage

    Polypeptides: Carboxypeptidase E
  10. Drug

    Atropine

    go.drugbank.com/drugs/DB00572
    ApprovedInvestigationalVet approved

    [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675] … Oral atropine is only available in combination products.

    Mixtures: B-Donna, Re-PB HyosProducts: Atropin Accord 0,1 mg/ml Injektionslösung in einer Fertigspritze, Atropinsulfat Aguettant 0,1 mg/ml Injektionslösung in Fertigspritze