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Displaying results 2691 - 2700 of 10000 in total
  1. Drug

    Fidaxomicin

    go.drugbank.com/drugs/DB08874
    ApprovedInvestigational

    Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months. … [L11575] Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation.

    Synonyms: Tiacumicin BCategories: P-glycoprotein substrates, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    Evolocumab is a human IgG2 monoclonal antibody that targets the proprotein convertase subtilisin/kexin type 9 (PCSK9). … PCSK9 is a protein that targets LDL receptors for degradation, therefore reducing the liver's ability to remove LDL-cholesterol (LDL-C), or "bad" cholesterol, from the blood.

    Products: REPATHA® 140 MG/ML, REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET
  3. Drug

    Plozasiran

    go.drugbank.com/drugs/DB18997
    ApprovedInvestigational

    Plozasiran (ARO-APOC3) is a small interfering RNA (siRNA) that degrades apolipoprotein C-III (apoC-III) mRNA by RNA interference. … Plozasiran contains a covalently linked ligand containing three N-acetylgalactosamine (GalNAc) residues to facilitate delivery to hepatocytes where it works to reduce triglyceride levels.

  4. Drug

    Adomeglivant

    go.drugbank.com/drugs/DB11704
    Investigational

    Adomeglivant has been investigated for the basic science of Type 2 Diabetes.

  5. Drug

    Dutogliptin

    go.drugbank.com/drugs/DB11723
    Investigational

    Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.

  6. Drug

    Monteplase

    go.drugbank.com/drugs/DB12726
    Investigational

    Monteplase has been used in trials studying the treatment of Pulmonary Embolism.

  7. Drug

    Firategrast

    go.drugbank.com/drugs/DB12732
    Investigational

    Firategrast has been used in trials studying the treatment of Multiple Sclerosis.

  8. Drug

    GW-493838

    go.drugbank.com/drugs/DB12760
    Investigational

    GW493838 has been used in trials studying the treatment of Neuropathic Pain.

  9. Drug

    Clazakizumab

    go.drugbank.com/drugs/DB12849
    Investigational

    Clazakizumab has been used in trials studying the treatment of Rheumatoid Arthritis.

  10. Drug

    Apricitabine

    go.drugbank.com/drugs/DB12855
    Investigational

    Apricitabine has been used in trials studying the treatment of HIV Infections.

    Categories: Heterocyclic Compounds, 1-Ring