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Papaya
go.drugbank.com/drugs/DB10658ApprovedPapaya allergenic extract is used in allergenic testing.
Mixtures: Alka-pan TabletsAcepromazine
go.drugbank.com/drugs/DB01614InvestigationalVet approvedAcepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Zileuton
go.drugbank.com/drugs/DB00744ApprovedWithdrawnSpecifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. … The immediate release tablet of Zileuton has been withdrawn from the US market.
4-(Isopropylamino)diphenylamine
go.drugbank.com/drugs/DB14195Approved4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen.
Lanolin alcohols
go.drugbank.com/drugs/DB14181ApprovedIt is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.
Elamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigationalFood and Drug Administration (FDA) granted accelerated approval for FORZINITY™ (elamipretide) to improve muscle strength in adult and pediatric patients with Barth syndrome weighing at least 30 kg.
Verteporfin
go.drugbank.com/drugs/DB00460ApprovedInvestigationalIt is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. … Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and [CL-315585].
Crotalus adamanteus antivenin
go.drugbank.com/drugs/DB13893ApprovedIt is intravenously administered to limit systemic toxicity [FDA label]. … Crotalus adamanteus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Crotalus adamanteus (Eastern Diamondback rattlesnake
Normethadone
go.drugbank.com/drugs/DB11609ApprovedIllicitNormethadone is used as an opioid antitussive in combination with [DB11610]. It is marketed in Canada by Valeant under the tradename Cophylac.
Perfluorohexyloctane
go.drugbank.com/drugs/DB17823ApprovedInvestigational[A259741] It was approved by the FDA on May 18, 2023 for the treatment of dry eye disease.[L46536] … [A259746, A259751] Perfluorohexyloctane has been used in the field of ophthalmology as a vitreous substitute.