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Displaying results 2721 - 2730 of 10000 in total
  1. Drug

    Technetium Tc-99m oxidronate

    go.drugbank.com/drugs/DB09139
    ApprovedWithdrawn

    [L1140] It was developed by Mallinkrodt nuclear and FDA approved on February 18, 1981. … [L1138] These complexes are formed by the binding of 99mTc to metal atoms of an organic molecule.

  2. Drug

    Lefamulin

    go.drugbank.com/drugs/DB12825
    Approved

    [A183206] Lefamulin is available in intravenous and oral preparations and was granted FDA approval in August 2019. … A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus.

  3. Drug

    Benzthiazide

    go.drugbank.com/drugs/DB00562
    Approved

    They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. … Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics).

    Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics
  4. Drug

    Eflepedocokin alfa

    go.drugbank.com/drugs/DB16366
    Investigational

    Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant … [A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).[L27666]

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSynonyms: F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO AN IMMUNOGLOBULIN CONSTANT REGION (IGG2-FC))
  5. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

  6. Drug

    Pentazocine

    go.drugbank.com/drugs/DB00652
    ApprovedVet approved

    It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)

    Mixtures: Pentazocine and naloxone, Pentazocine and naloxoneCategories: pentazocine and naloxone
  7. Drug

    Ropeginterferon alfa-2b

    go.drugbank.com/drugs/DB15119
    ApprovedInvestigational

    [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life. … [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  8. Drug

    LetibotulinumtoxinA

    go.drugbank.com/drugs/DB16820
    Approved

    [L42335] It was approved for use in the treatment of glabellar lines in Canada in June 2022[L42330,L42335] and in the US in March 2024.[L50291,L50296] … [A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since become one of the most popular cosmetic procedures worldwide.

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and Proteins
  9. Target

    Potassium-transporting ATPase ATP-binding subunit

    go.drugbank.com/bio_entities/BE0003296
    TargetEscherichia coli (strain K12)

    This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm (PubMed:16354672, PubMed:30478378, PubMed:34272288).

    Synonyms: Potassium-binding and translocating subunit B
  10. Target

    Myosin light chain 6B

    go.drugbank.com/bio_entities/BE0004292
    TargetHumans

    Regulatory light chain of myosin. Does not bind calcium

    Synonyms: Smooth muscle and nonmuscle myosin light chain alkali 6B