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Vorasidenib
go.drugbank.com/drugs/DB17097ApprovedInvestigationalVorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor. … [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)-Cinnamyl alcohol
go.drugbank.com/drugs/DB14186ApprovedCinnamyl alcohol is a naturally occurring compound that is found within cinnamon. … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266]. Sensitivity to cinnamyl alcohol may be identified with a clinical patch test.
Synonyms: (2E)-3-phenylprop-2-en-1-ol, (E)-cinnamyl alcoholChloride ion
go.drugbank.com/drugs/DB14547InvestigationalSynonyms: Chloride(1-)Mixtures: Telom-X-gene, SH NEOLPHARThiohexam
go.drugbank.com/drugs/DB14200ApprovedThiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: N-cyclohexyl-2-Benzothiazosulfenamide, 2-Benzenethiazolesulfenamide, N-cyclohexyl-Zinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: Diphenhydramine D, CALPRAX CLEAR®Synonyms: Zinc(II) acetateGallium chloride Ga-67
go.drugbank.com/drugs/DB14550ApprovedGallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with [sodium citrate] to generate [gallium citrate Ga 67], which can be used to image certain cancers
Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. … [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849]
Synonyms: L-6-(18F)Fluoro-DOPA, 6-Fluoro-(18F)-L-3,4-DihydroxyphenylalanineDiphenylguanidine
go.drugbank.com/drugs/DB14191ApprovedIt is also a dermatological sensitizer and allergen. Sensitivity to diphenylguanidine may be identified with a clinical patch test. … Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber products.
Synonyms: s-Diphenylguanidine, N,N'-diphenylguanidineInternational brands: Soxinol D, Nocceler DN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine
go.drugbank.com/drugs/DB14196ApprovedN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. … Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Synonyms: N-Cyclohexyl-N'-phenyl-p-phenylendiamine, N-cyclohexyl-N'-phenyl-p-phenylenediamine