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Displaying results 2751 - 2760 of 10000 in total
  1. Drug

    Binimetinib

    go.drugbank.com/drugs/DB11967
    ApprovedInvestigational

    Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: MEKTOVI® 15 MG TABLETAS RECUBIERTAS
  2. Drug

    N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine

    go.drugbank.com/drugs/DB14196
    Approved

    N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. … Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.

    Synonyms: N-Cyclohexyl-N'-phenyl-p-phenylendiamine, N-cyclohexyl-N'-phenyl-p-phenylenediamine
  3. Drug

    Diphenylguanidine

    go.drugbank.com/drugs/DB14191
    Approved

    It is also a dermatological sensitizer and allergen. Sensitivity to diphenylguanidine may be identified with a clinical patch test. … Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber products.

    Synonyms: s-Diphenylguanidine, N,N'-diphenylguanidineInternational brands: Soxinol D, Nocceler D
  4. Drug

    Bromocriptine

    go.drugbank.com/drugs/DB01200
    ApprovedInvestigationalWithdrawn

    Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. … Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 2-bromo-α-ergokryptin, 2-bromo-α-ergocryptine
  5. Drug

    Prednisolone phosphate

    go.drugbank.com/drugs/DB14631
    ApprovedInvestigationalVet approved

    Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

    Mixtures: OFTALETYC® NFCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2A6 Inducers
  6. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Synonyms: Zinc(II) acetateMixtures: Diphenhydramine D, CALPRAX CLEAR®
  7. Drug

    Certolizumab pegol

    go.drugbank.com/drugs/DB08904
    ApprovedInvestigational

    [A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha).

    Products: CIMZIA®, CIMZIA 200MG PAT F DOSIERG
  8. Drug

    Etrolizumab

    go.drugbank.com/drugs/DB12189
    Investigational

    [A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some success and include approved drugs such as … Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration

  9. Drug

    Levopropoxyphene

    go.drugbank.com/drugs/DB06793
    ApprovedWithdrawn

    Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. … This drug presented different dosages and it was administered as a capsule or suspension.

    Synonyms: (l)-Propoxyphene
  10. Drug

    4-(Isopropylamino)diphenylamine

    go.drugbank.com/drugs/DB14195
    Approved

    4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. … Sensitivity to this compound may be identified with a clinical patch test.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-Fenyl-N'-isopropyl-p-fenylendiamin, 1,4-Benzenediamine, N-(1-methylethyl)-N'-phenyl-