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Allergic Diseases
go.drugbank.com/conditions/DBCOND0110864Drugs: Acetaminophen · Ammonium chloride · Betamethasone phosphate · Brompheniramine · Buclizine · Budesonide +17 moreSynonyms: Other and unspecified allergy, Atopic AND/OR hypersensitivity statePivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalIt is active against gram-negative organisms and used as for amdinocillin. [PubChem] … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Diroximel fumarate
go.drugbank.com/drugs/DB14783ApprovedInvestigationalDiroximel fumarate was formulated by Alkermes in collaboration with Biogen, and was approved by the FDA in October 2019[L9626] and by the EMA in November 2021.[L39225] … Relapsing-remitting forms of MS lead to neurological symptoms that resolve and recur periodically. More than 80% of patients suffering from this disease have relapsing-remitting MS.
Categories: Antineoplastic and Immunomodulating AgentsNeurological Manifestations
go.drugbank.com/conditions/DBCOND0031286Synonyms: Neurologic Signs and Symptoms, Neurological signs and symptoms NECDonidalorsen
go.drugbank.com/drugs/DB18751ApprovedInvestigational[A274308] Donidalorsen is a ligand-conjugated antisense oligonucleotide that reduces plasma prekallikrein production, thereby reducing bradykinin production and preventing the initiation of attacks. … Hereditary angioedema (HAE) is a rare genetic disease characterized by recurrent episodes of severe swelling induced by excessive production of bradykinin.
Categories: Nucleic Acids, Nucleotides, and NucleosidesGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.
Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsInsulin pork
go.drugbank.com/drugs/DB00071ApprovedInsulin isolated from pig pancreas. Composed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsLonidamine
go.drugbank.com/drugs/DB06266InvestigationalIn such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs. … Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
Categories: Antineoplastic and Immunomodulating AgentsTechnetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnfor liver uptake) as are other tracers from the iminodiacetic acid. … It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary
Categories: Indicators and Reagents, Amino Acids, Peptides, and ProteinsLipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedNeutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur from myelosuppressive anticancer treatments [A32665]. … PEG moiety protects the active molecule from enzyme degradation, which allows longer half-life of drug and less frequent dosing-schedule in addition to acceptable safety and efficacy profile [A32665].
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents