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Nivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: Immunoglobulin G, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[A256708] Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical … [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other side effects, notably gastrointestinal hypomotility and orthostatic hypotension. [L905,A215552].
Categories: Adrenergic alpha-1 Receptor Antagonists, Diazepines, Oxazepines, Thiazepines and OxepinesProducts: CLONEX 100 MG TABLET, 50 ADET, LEPONEX 100 MG TABLET, 50 ADETTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.
Categories: Drugs for Treatment of Hyperkalemia and Hyperphosphatemia, Compounds used in a research, industrial, or household settingSynonyms: poly(styrene-4-sulfonic acid)Prednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Mixtures: BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.
Mixtures: PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML, CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 MLCategories: Adrenergic alpha-1 Receptor Agonists, Mydriatics and CycloplegicsPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Pemetrexed Zentiva 10 mg/ml Infusionslösung, ALIMTA INFUZYON COZELTISI ICIN TOZ ICEREN FLAKON 10 ML, 1 ADETTuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with *Mycobacterium tuberculosis* through early diagnosis and appropriate
Categories: Compounds used in a research, industrial, or household setting, Indicators and ReagentsProducts: BIOCINE TESTPPD 5-UI/ 01 ML, PPD TÜBERKÜLIN 5 TU/ 0.1 ML INTRADERMAL ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADETDapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalA sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Mixtures: Dapsone 6% / Niacinamide 2% / Spironolactone 5%, Dapsone 8.5% / Niacinamide 2% / Spironolactone 5%Categories: dapsone and rifampicin, dapsone, rifampicin and clofazimineVecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalA non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or
Categories: P-glycoprotein substratesProducts: NORCURON 10 MG, VECRON 10 MG İ.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPULSecalciferol
go.drugbank.com/drugs/DB18406ExperimentalSynonyms: 2,3-heptanediol, 2-methyl-6-((1r,3as,4e,7ar)-octahydro-4-((2z)-2-((5s)-5-hydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyl-1h-inden-1-yl)-, (3r,6r)-, (5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-3b,24,25-triol