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Primary amine oxidase
go.drugbank.com/bio_entities/BE0001222TargetEnzymeEscherichia coli (strain K12)The enzyme prefers aromatic over aliphatic amines.
Synonyms: Copper amine oxidaseDoripenem
go.drugbank.com/drugs/DB06211ApprovedWithdrawn, resulting in a premature termination of the trial. … The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved indications.
Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalProducing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. … The potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation.
Synonyms: 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamideHuman vaccinia virus immune globulin
go.drugbank.com/drugs/DB14112ApprovedInvestigationalwho possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. … Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine
Eliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigationalEliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease. … [L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease.
Succinic acid
go.drugbank.com/drugs/DB00139ApprovedInvestigationalNutraceuticalIt is also used in foods as a sequestrant, buffer, and a neutralizing agent. … A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters.
Mixtures: FeRiva 21-7 28-Day, Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic AcidNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
go.drugbank.com/bio_entities/BE0000224TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-MWFENADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
go.drugbank.com/bio_entities/BE0000245TargetHumansAccessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. … Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain
Synonyms: Complex I-PDSWNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
go.drugbank.com/bio_entities/BE0000284TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B12NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
go.drugbank.com/bio_entities/BE0000313TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-KFYI