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Displaying results 2771 - 2780 of 10000 in total
  1. Indication

    Toxocariasis

    go.drugbank.com/conditions/DBCOND0009840
    Drugs: Mebendazole
    Synonyms: Infection due to toxocara
  2. Drug

    13-deoxydoxorubicin

    go.drugbank.com/drugs/DB05706
    Investigational

    GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.

  3. Indication

    Rocky Mountain Spotted Fever

    go.drugbank.com/conditions/DBCOND0000434
    Drugs: Minocycline · Tetracycline
    Synonyms: Spotted fever due to Rickettsia rickettsii, Spotted fever due to Rickttsia rickettsii
  4. Indication

    Opioid Overdose

    go.drugbank.com/conditions/DBCOND0058333
    Drugs: Nalmefene · Naloxone
    Synonyms: Toxicity to various agents
  5. Drug

    Iopodic acid

    go.drugbank.com/drugs/DB09333
    ApprovedWithdrawn

    On September 22, 1981, ipodate was submitted again by the company Schering AG but it is currently under an inactive status.[L1082] … [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque property. It was developed and filed to the FDA by the company BRACCO.

  6. Drug

    Pancrelipase amylase

    go.drugbank.com/drugs/DB11065
    ApprovedInvestigational

    [T177] The pancrelipase amylase is a single polypeptide chain containing two SH groups and four disulfide bridges. … [L2509] The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch into more available saccharide forms.

    Mixtures: Pancrease Mt 10, Creon 10 Minimicrospheres
  7. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    Two years later, the research group isolated a compound structurally similar to hydroxymethylglutarate (HMG) that inhibited the incorporation of acetate. … During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels.

  8. Drug

    Bemotrizinol

    go.drugbank.com/drugs/DB11206
    Approved

    Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity [A19212]. … It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application [A19212, A32909].

    Mixtures: The History Of Whoo Gongjinhyang Mi Pact 2, The History Of Whoo Gongjinhyang Mi Pact 1
  9. Drug

    Mannitol busulfan

    go.drugbank.com/drugs/DB12097
    ApprovedWithdrawn

    Mm has been used in trials studying the treatment of Cocaine Dependence and Diabetes Mellitus, Type 2.

  10. Drug

    Zoliflodacin

    go.drugbank.com/drugs/DB12817
    ApprovedInvestigational

    Gonorrhea, caused by Neisseria gonorrhoeae, presents a significant public health challenge due to increasing antimicrobial resistance. … [A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates