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Tasimelteon
go.drugbank.com/drugs/DB09071ApprovedInvestigationalIn blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. … Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Synonyms: N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamideTAK-428
go.drugbank.com/drugs/DB05499ExperimentalIt is based on the novel concept that peripheral nervous tissue that was damaged by diabetes can be repaired and regenerated by stimulating an increase in neurotrophic factors.
Glibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Drugs Used in DiabetesDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approved[L42880] It is a second-generation tetracycline that was first discovered in 1967.[A19429] Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines.
Lumiracoxib
go.drugbank.com/drugs/DB01283ApprovedWithdrawnNew Zealand and Canada have also followed suit in recalling the drug. … On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver
Thrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalMedical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. … Failure to clot blood occurs in the rare case where the primary clotting defect is the absence of fibrinogen itself.
Griseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Ixekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIn particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid Arthritis and plaque psoriasis. … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions.
Products: Taltz 80mg solution for injection in pre-filled pen, TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/mlTenecteplase
go.drugbank.com/drugs/DB00031ApprovedInvestigationalamino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in
Vecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalIts lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or