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Cisatracurium
go.drugbank.com/drugs/DB00565ApprovedInvestigationalCisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate. … Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine.
Synonyms: Cisatracurium ionTolazamide
go.drugbank.com/drugs/DB00839ApprovedA sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Enzalutamide
go.drugbank.com/drugs/DB08899ApprovedInvestigational[L40639] It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012. … Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic.
Categories: Antiandrogens, non-steroidalThromboembolism
go.drugbank.com/conditions/DBCOND0022145Prophylaxis of Pulmonary embolism
go.drugbank.com/conditions/DBCOND0022149Ivacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigationalIt was approved by the Food and Drug Administration on January 31, 2012[L768], and by Health Canada in late 2012. … Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and consequently abnormal fluid and ion transport across cell membranes.
Taletrectinib
go.drugbank.com/drugs/DB18711ApprovedInvestigational[L53308] Gene fusions involving _ROS1_, a proto-oncogene, have been identified as oncogenic drivers in 1-2% of patients with non-small cell lung cancer (NSCLC), in addition to other cancers at variable
Choline magnesium trisalicylate
go.drugbank.com/drugs/DB01401ApprovedCholine magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … [L43652] It is also being investigated in other cancers, such as colon cancer, pancreatic cancer, non-small cell lung cancer (NSCLC), and malignant melanoma.
Pentetic acid
go.drugbank.com/drugs/DB14007ApprovedInvestigationalPentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable … DTPA-metal ion complexes.