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Displaying results 2791 - 2800 of 10000 in total
  1. Drug

    Odesivimab

    go.drugbank.com/drugs/DB15900
    ApprovedInvestigational

    [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … All three mAbs bind to a distinct portion of the GP<sub>1,2</sub> glycoprotein and collectively provide neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against

  2. Drug

    ISO-1 F-18

    go.drugbank.com/drugs/DB14900
    Investigational

    ISO-1 F-18 is under investigation in clinical trial NCT00968656 (Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1).

    Synonyms: F-18-ISO, [18F]ISO-1
  3. Drug

    Girentuximab I-124

    go.drugbank.com/drugs/DB15025
    Investigational

    Girentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).

    Synonyms: Girentuximab I-124, Iodine i 124 girentuximab
  4. Drug

    Levocetirizine

    go.drugbank.com/drugs/DB06282
    ApprovedInvestigational

    Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine]. … [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694]

    Synonyms: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acidMixtures: NORAVER ® GFAST CAPSULAS BLANDAS CONTRA LOS SINTOMAS DE LA GRIPA, BREATHEZY - L
  5. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring. … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile, fosfomycin has largely become a first-line therapeutic option for the treatment of uncomplicated

    Synonyms: L-cis-1,2-epoxypropylphosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acidProducts: FOSFOMICINA EG, FOSTREN® 3 G
  6. Drug

    Glycopyrronium

    go.drugbank.com/drugs/DB00986
    ApprovedInvestigationalVet approved

    [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.

    Mixtures: TRIMBOW PRESSURISED INHALATION SOLUTION 100/6/12.5 μg PER ACTUATION, TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 Substrates
  7. Pathway

    Indomethacin Action Pathway

    smpdb.ca/view/SMP0000104
    Drug action

    Indomethacin (also named Amuno or Indocid) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat prostaglandin G/H synthase related fever, swelling, pain and inflammation. Indomethacin can block prostaglandin synthesi...

    Drugs: Glutamic acid · Glutathione · Indomethacin · Dinoprostone · Calcium · Magnesium cation +5 more
    Enzymes: Prostaglandin E synthase
  8. Drug

    CPD 923

    go.drugbank.com/drugs/DB05856
    Experimental

    CPD 923 (N-butylgalactonorjirimycin) is an iminosugar and an analogue of ZavescaTM. It shows efficacy in vivo studies, as well as a favourable pre-clinical tolerability profile.

  9. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    Product which allowed it to have a status a priority review. … Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]

    Mixtures: RIFETEM 250 MG / 3 ML AMPUL, 1 ADET, RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (1 AMPUL)Categories: MATE 1 Inhibitors, P-glycoprotein inhibitors
  10. Drug

    Maftivimab

    go.drugbank.com/drugs/DB15899
    ApprovedInvestigational

    [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … All three mAbs bind to a distinct portion of the GP<sub>1,2</sub> glycoprotein and collectively provide neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against