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Displaying results 2791 - 2800 of 10000 in total
  1. Target

    Metal cation symporter ZIP8

    go.drugbank.com/bio_entities/BE0009901
    TransporterHumans

    Also indirectly regulates the expression of proteins involved in cell morphology and cytoskeleton organization (PubMed:29927450). … Through zinc import, indirectly regulates the metal-dependent transcription factor MTF1 and the expression of some metalloproteases involved in cartilage catabolism and also probably heart development

    Synonyms: Zrt- and Irt-like protein 8, BCG-induced integral membrane protein in monocyte clone 103 protein
  2. Drug

    Collagenase clostridium histolyticum

    go.drugbank.com/drugs/DB00048
    ApprovedInvestigational

    Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease.

    Categories: Enzymes and Coenzymes, Skin and Mucous Membrane Agents
  3. Drug

    Hetacillin

    go.drugbank.com/drugs/DB00739
    ApprovedVet approvedWithdrawn

    Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.

  4. Indication

    Proliferative Diabetic Retinopathy (PDR)

    go.drugbank.com/conditions/DBCOND0056889
    Drugs: Ranibizumab
    Synonyms: Retinopathy co-occurrent and due to diabetes mellitus, Proliferative retinopathy co-occurrent and due to diabetes mellitus
  5. Drug

    Turpentine

    go.drugbank.com/drugs/DB11120
    Approved

    It is used as a solvent and base material in organic synthesis reactions. … Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene with lesser amounts of carene, camphene, dipentene, and terpinolene.

    Mixtures: Cal Mo Dol Ont, Jack and Jill RubCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Cyanocobalamin Co-60

    go.drugbank.com/drugs/DB09387
    ApprovedWithdrawn

    Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons. … Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60.

  7. Indication

    Venous Embolism

    go.drugbank.com/conditions/DBCOND0133256
    Drugs: Phenprocoumon
    Synonyms: Acute embolism and thrombosis of unspecified vein
  8. Drug

    Misoprostol

    go.drugbank.com/drugs/DB00929
    ApprovedInvestigational

    [L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the … strength and frequency of contractions and decrease cervical tone.

    Mixtures: Diclofenac Sodium and Misoprostol, Diclofenac Sodium and MisoprostolCategories: naproxen and misoprostol, Alimentary Tract and Metabolism
  9. Drug

    Ebola Zaire vaccine (live, attenuated)

    go.drugbank.com/drugs/DB15595
    ApprovedInvestigational

    [L10854] Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease. … [L10866] In non-human primate clinical trials, the vaccine was effective in inducing an immune response against the Ebola viruses.

  10. Drug

    Metreleptin

    go.drugbank.com/drugs/DB09046
    ApprovedInvestigational

    [L41315] In February 2014, metreleptin was approved by the FDA for the treatment of complications of leptin deficiency, as an adjunct to diet, in patients with congenital generalized or acquired generalized … Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine residue at its amino terminus.

    Categories: Amino Acids and Derivatives, Alimentary Tract and MetabolismSynonyms: N-Methionylleptin