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Displaying results 2801 - 2810 of 3732 in total

Drug
Dicloxacillin
go.drugbank.com/drugs/DB00485
ApprovedInvestigationalVet approved
One of the penicillins which is resistant to penicillinase.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
Drug
Pefloxacin
go.drugbank.com/drugs/DB00487
Approved
A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Zidovudine
go.drugbank.com/drugs/DB00495
ApprovedInvestigational
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid c...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
Drug
Darifenacin
go.drugbank.com/drugs/DB00496
ApprovedInvestigational
It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
Drug
Triflupromazine
go.drugbank.com/drugs/DB00508
ApprovedVet approved
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Categories: P-glycoprotein inhibitors, Dopamine D2 Receptor Antagonists
Drug
Albendazole
go.drugbank.com/drugs/DB00518
ApprovedInvestigationalVet approved
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
Drug
Alitretinoin
go.drugbank.com/drugs/DB00523
Approved
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess o...
Categories: P-glycoprotein substrates
Drug
Mephenytoin
go.drugbank.com/drugs/DB00532
ApprovedWithdrawn
Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Rofecoxib
go.drugbank.com/drugs/DB00533
ApprovedWithdrawn
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belong...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
Drug
Ciprofloxacin
go.drugbank.com/drugs/DB00537
ApprovedInvestigational
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections. The first...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inhibitors