Search

Displaying results 2821 - 2830 of 10000 in total
  1. Drug

    Omaveloxolone

    go.drugbank.com/drugs/DB12513
    ApprovedInvestigational

    [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. … Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.

    Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 SubstratesSynonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-
  2. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384]

    Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline, [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-prolineMixtures: LisAm 20 mg/5 mg Tabletten, AMLIPIN 5 / 5 MG FILM TABLET, 30 ADET
  3. Drug

    Calcium ascorbate

    go.drugbank.com/drugs/DB14483
    ApprovedNutraceutical

    Mixtures: Supplements De Vitamines Et Mineraux, For-2Categories: Vitamin C and analogues, Compounds used in a research, industrial, or household setting
  4. Drug

    Mepyramine

    go.drugbank.com/drugs/DB06691
    ApprovedVet approved

    It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. … It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions.

    Mixtures: PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 24 ADET, PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 40 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 Inhibitors
  5. Drug

    Amiloxate

    go.drugbank.com/drugs/DB11207
    Approved

    Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m [F35]. … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916].

    Mixtures: Ruby-Cell 4U Plus Sun, Dpc Pink Aura Cushion No.21Synonyms: 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester, Isoamyl p-methoxycinnamate
  6. Drug

    Teniposide

    go.drugbank.com/drugs/DB00444
    ApprovedInvestigational

    Teniposide acts primarily in the G2 and S phases of the cycle. … Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.

    Synonyms: 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  7. Drug

    Threonine

    go.drugbank.com/drugs/DB00156
    ApprovedInvestigationalNutraceutical

    An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.

    Mixtures: TRAVASOL PLUS 15% LIBRE DE BISULFITO, TRAVASOL PLUS 15% LIBRE DE BISULFITOSynonyms: L-2-Amino-3-hydroxybutyric acid, 2-Amino-3-hydroxybutyric acid
  8. Drug

    Carboprost

    go.drugbank.com/drugs/DB19356
    Approved

    Synonyms: (e,z)-(1r,2r,3r,5s)-7-(3,5-dihydroxy-2-((3s)-(3-hydroxy-3-methyl-1-octenyl))cyclopentyl)-5-heptenoic acid, (15s)-15-methylprostaglandin f(sub 2.alpha.)Categories: Prostaglandins F, Synthetic
  9. Drug

    Lisaftoclax

    go.drugbank.com/drugs/DB18054
    Investigational

    Lisaftoclax is a novel, orally active, selective and potent BCL-2 inhibitor

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(4-((6-(4-chlorophenyl)spiro(3.5)non-6-en-7-yl)methyl)-piperazin-1-yl)-n-((3-nitro-4-(((2s)-1,4-dioxan-2-ylmethyl)amino)phenyl)sulfonyl)-2-(1hpyrrolo(2,3-b)pyridin-5-yloxy)benzamide, 4-{4-{[6-(4-Chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl}-piperazin-1-yl}-N-{{3-nitro-4-[((2S)-1,4-dioxan-2-ylmethyl)amino]phenyl}sulfonyl}-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
  10. Drug

    Mitotane

    go.drugbank.com/drugs/DB00648
    ApprovedInvestigational

    Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and

    Synonyms: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene, o,p'-DDDCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inducers