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Sipuleucel-T
go.drugbank.com/drugs/DB06688ApprovedInvestigationalSipuleucel-T is marketed under the brand name Provenge by Dendreon Corporation. Sipuleucel-T was approved by the U.S. … The treatment initially cost $93,000 at the time of FDA approval, but rose to over $100,000 in 2014.
Synonyms: Sipuleucel-TCategories: sipuleucel-TAntilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalThe result is polyclonal IgG that is then purified from the horse's serum to produce a usable drug product that can be used for immunosuppression. … Equine ATG is currently indicated for the suppression of the immune system to prevent renal transplant rejection and in the treatment of aplastic anemia.
Categories: Increased T Lymphocyte DestructionSynonyms: e-ATGPotassium bitartrate
go.drugbank.com/drugs/DB11107ApprovedInvestigationalPotassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. … It is obtained as a byproduct of wine manufacture during the fermentation process.
Sulfanilamide
go.drugbank.com/drugs/DB00259ApprovedWithdrawnSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Meclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigational[L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets. … It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases.
Bentiromide
go.drugbank.com/drugs/DB00522ApprovedWithdrawnCases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is currently not available in the U.S. or Canada. … Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy.
Deuruxolitinib
go.drugbank.com/drugs/DB18847ApprovedInvestigationalDeuteration allows the drug to circumvent extensive oxidative metabolism around the cyclopentyl ring, which increases the duration of the pharmacological activity of deuruxolitinib. … [L51083] Alopecia areata is an autoimmune condition that attacks the hair follicles and leads to unpredictable hair loss in the scalp and other areas of the body.
Magnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnIt also has antacid properties and is used as a component of some over the counter antacid medications. … Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group [A32782].
Alogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalChemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Penicillium italicum
go.drugbank.com/drugs/DB10811ApprovedPenicillium italicum is a fungus which can provoke allergic reactions. Penicillium italicum extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture