Search
Belimumab
go.drugbank.com/drugs/DB08879ApprovedInvestigational[L42630] Belimumab was first approved by the FDA on March 9, 2011,[A251495] making it the newest drug to be approved for the treatment of SLE in more than 50 years. … Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor.
Products: Benlysta Powder for Solution for Infusion 400mg, Benlysta Powder for Solution for Infusion 120mgCatridecacog
go.drugbank.com/drugs/DB09310ApprovedFor people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and prevention of bleeding episodes … When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation of the catalytic A-subunit and dissociation from its carrier B-subunit.
Synonyms: Factor XIII A-Subunit (Recombinant), Coagulation Factor XIII A-Subunit (recombinant)Maxy-G34
go.drugbank.com/drugs/DB05718InvestigationalIt is being developed by Maxygen, Inc. for the treatment of chemotherapy-induced neutropenia. … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF).
Categories: Compounds used in a research, industrial, or household settingNirogacestat
go.drugbank.com/drugs/DB12005ApprovedInvestigationalNirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … 3 DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo.
Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnThe FDA issued a warning letter regarding this risk to health care professionals and patients. … In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Categories: Drugs for Functional Gastrointestinal DisordersClonixin
go.drugbank.com/drugs/DB09218InvestigationalClonixin is a non-steroidal anti-inflammatory drug.
Mixtures: PRESTOFLAM LD, PRESTOFLAM LDVirus Specific T-Cell
go.drugbank.com/drugs/DB15735InvestigationalVirus Specific T-Cells (VSTs) are a target therapy that are generated for specific viral antigens. These products are generated from virus-naive or virus-experienced autologous or allogenic sources. … These T-cells are then isolated from the donor and expanded in a culture to generate more VSTs.
Synonyms: HLA-matched Virus Specific T Cells, Partially HLA-matched Virus Specific T CellZaleplon
go.drugbank.com/drugs/DB00962ApprovedIllicitZaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. … Zaleplon is a schedule IV drug in the United States.
Synonyms: 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilideCategories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor AgonistTricaine
go.drugbank.com/drugs/DB11552ExperimentalVet approvedTricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish. … It is also the only anesthetic licensed in the United States for use in fin fish that are intended for human consumption.
Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
go.drugbank.com/drugs/DB14106ApprovedInvestigationalTetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]
Products: Kit for the Preparation of Technetium Tc99m Sestamibi, Stamicis Kit for Radiopharmaceutical Preparation 1mg