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Displaying results 2851 - 2860 of 10000 in total
  1. Drug

    Asfotase alfa

    go.drugbank.com/drugs/DB09105
    ApprovedInvestigational

    Asfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28, 2015, and was approved … Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc. The annual average price of Asfotase Alfa treatment is $285,000.

    Products: STRENSİQ 40 MG/1.0 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET, STRENSİQ 18 MG/0.45 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET
  2. Drug

    Etidronic acid

    go.drugbank.com/drugs/DB01077
    ApprovedInvestigational

    [A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901] … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].

    Synonyms: 1-Hydroxy-1,1-diphosphonoethane, (1-Hydroxyethylene)diphosphonic acidProducts: DIDRONAT 400 MG TABLET, 30 ADET, DIDRONAT 200 MG TABLET, 60 ADET
  3. Drug

    Lomitapide

    go.drugbank.com/drugs/DB08827
    Approved

    [A275445, A7367] This makes it a critical therapeutic option for "receptor-negative" patients who have little to no functional LDL receptor activity. … Lomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP).

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 SubstratesSynonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDE
  4. Drug

    Doxapram

    go.drugbank.com/drugs/DB00561
    ApprovedInvestigationalVet approved

    A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
  5. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    [A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 for hygienic use and sanitation for cholera infection. … Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight.

    Synonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-oneProducts: BİZMOPEPTOL MAX 1050 MG/30 ML ORAL SÜSPANSİYON, 240 ML, Up and Up 5-symptom Digestive Relief
  6. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    [L13571] It is therefore not considered to be a disease-modifying drug. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease

    Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Plerixafor

    go.drugbank.com/drugs/DB06809
    ApprovedInvestigational

    [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved by the US Food and Drug Administration on December 15, 2008.[A7117,L45678] … [A7117] Compared to placebo with G-CSF, the plerixafor and G-CSF mobilization regimen has a higher probability of achieving the optimal CD34+ cell target for tandem transplantation in fewer apheresis procedures

    Products: Mozofor 24 mg/1,2 mL S.C. Enjeksiyonluk Çözelti, 1 ADET, Lexeva 24 mg/1,2 mL S.C. Enjeksiyonluk Çözelti, 1 adet
  8. Drug

    Vilazodone

    go.drugbank.com/drugs/DB06684
    ApprovedInvestigational

    Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622].

    Categories: Serotonin 5-HT1 Receptor Agonists, Cytochrome P-450 SubstratesProducts: ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET, ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET
  9. Drug

    JNJ-28312141

    go.drugbank.com/drugs/DB17140
    Experimental

    Synonyms: 1h-imidazole-2-carboxamide, 5-cyano-n-(2-(1-cyclohexen-1-yl)-4-(1-(2-(dimethylamino)acetyl)-4-piperidinyl)phenyl)-, 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamideCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Larotrectinib

    go.drugbank.com/drugs/DB14723
    ApprovedInvestigational

    On April 10, 2025, the FDA granted full drug approval.[L52805] … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: VITRAKVI 100 MG SERT KAPSÜL, 56 ADET, VITRAKVI 25 MG SERT KAPSÜL, 56 ADET