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Streptococcus pneumoniae type 10a capsular polysaccharide antigen
go.drugbank.com/drugs/DB10329ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia. … Streptococcus pneumoniae type 10a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 10a of *Streptococcus pneumoniae
Mixtures: PNEUMOVAX 23 Injektionslösung in einer Fertigspritze, PNEUMOVAX 23 Injektionslösung in einer DurchstechflascheStreptococcus pneumoniae type 11a capsular polysaccharide antigen
go.drugbank.com/drugs/DB10330ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia. … Streptococcus pneumoniae type 11a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 11a of *Streptococcus pneumoniae
Mixtures: PNEUMOVAX 23 Injektionslösung in einer Fertigspritze, PNEUMOVAX 23 Injektionslösung in einer DurchstechflascheGlymidine
go.drugbank.com/drugs/DB01382ApprovedThe mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral … Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin.
Categories: Drugs Used in Diabetes, combinations of sulfonamidesOmega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalThe three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) (both commonly found in … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.
Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: Animi-3 with Vitamin D, LIPOPLUS 20% ( EMULSION PARA PERFUSION IV.)Crofelemer
go.drugbank.com/drugs/DB04941ApprovedInvestigationalCrofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree <i>Croton lechleri</i>. … It is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingInternational brands: ProvirOmidubicel
go.drugbank.com/drugs/DB17132ApprovedInvestigationalIn addition, the fact that 39% of the study's cohort were non-White patients highlights the importance of this type of treatment in key demographics with low donor availability. … In this group of patients, umbilical cord blood can be used as an alternative cell source since there is a lower risk of graft failure or graft-versus-host disease, even with low-grade HLA-matching.
MLN576
go.drugbank.com/drugs/DB06517ExperimentalXR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]
Categories: Topoisomerase I Inhibitors, Topoisomerase II InhibitorsLaromustine
go.drugbank.com/drugs/DB05817InvestigationalVNP40101M is a novel alkylating agent that has been used in trials studying the treatment of Leukemia, Lymphoma, Lung Cancer, Small Intestine Cancer, and Myelodysplastic Syndromes, among others.
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 SubstratesAmsilarotene
go.drugbank.com/drugs/DB21085InvestigationalAmsilarotene is under investigation in clinical trial NCT00687596 (Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy … Amsilarotene has a monoisotopic molecular weight of 385.15 Da.
Mechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigational) in patients who have received prior skin-directed therapy. … The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
Categories: Compounds used in a research, industrial, or household setting, Weapons of Mass DestructionSynonyms: β,β'-dichlorodiethyl-N-methylamine, N-methyl-bis(2-chloroethyl)amine