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Lovotibeglogene autotemcel

Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β^A-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding … have a history of vaso-occlusive events.

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.

Amikacin

Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. … [FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A.

Benzyl alcohol

Tetraethylammonium

The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels. … The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued.

Omadacycline

Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent

Clinafloxacin

Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties.

Tebipenem pivoxil

Tebipenem pivoxil is an orally administered prodrug of tebipenem, a carbapenem antibacterial that kills bacteria by binding essential penicillin-binding proteins and disrupting cell wall biosynthesis. … [L57980] Tebipenem pivoxil is the first oral carbapenem approved in the United States, creating an outpatient option for patients who have limited or no alternative oral therapy.

Phosphocreatine

It is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contractions via its ability to … Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine.

Talniflumate

Phase I trials with talniflumate for the treatment of cystic fibrosis and COPD were completed in August 2001, and phase II trials were performed in Ireland for the treatment of cystic fibrosis but this … Talniflumate, is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma [L1400].