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Displaying results 281 - 290 of 2454 in total
  1. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    Tyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.

    Synonyms: (S)-3-(p-Hydroxyphenyl)alanine, (−)-α-amino-p-hydroxyhydrocinnamic acidMixtures: Aminosyn-PF, Aminosyn-PF
  2. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of AC...

    Mixtures: RAMIPRIL HEXAL PL AM 5/5, RAMIPRIL HEXAL PL AM 5/5Products: RAMIPRIL DOC GENERICI, RAMIPRIL MYLAN GENERICS
  3. Drug

    Valine

    go.drugbank.com/drugs/DB00161
    ApprovedInvestigationalNutraceutical

    Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

    Mixtures: Aminosyn-PF, Aminosyn-PF
  4. Drug

    Erlotinib

    go.drugbank.com/drugs/DB00530
    ApprovedInvestigational

    Recent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and other myeloproliferative disorders.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: Aminosyn-PF, Aminosyn-PF
  6. Drug

    Sodium acetate

    go.drugbank.com/drugs/DB09395
    ApprovedInvestigational

    Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acet...

    Mixtures: Isolyte S pH 7.4, Isolyte P in Dextrose
  7. Drug

    Cladosporium cladosporioides

    go.drugbank.com/drugs/DB10431
    Approved

    Cladosporium cladosporioides is a fungus which can provoke allergic reactions. Cladosporium cladosporioides extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  8. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Inducers
  9. Drug

    Thonzylamine

    go.drugbank.com/drugs/DB11235
    Approved

    Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.

    Mixtures: Nasopen PE, Poly Hist PD
  10. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates