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Displaying results 281 - 290 of 10000 in total
  1. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. … Natural penicillins have limited activity against gram negative organisms; however, they may be used in some cases to treat infections caused by *Neisseria meningitidis* and *Pasteurella*.

    Synonyms: Free penicillin II, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: PENCAIN K-800 İ.Ü. IM ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL, PENCAIN K-400 İ.Ü. ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL
  2. Drug

    Meningococcal polysaccharide vaccine group C

    go.drugbank.com/drugs/DB13890
    ApprovedInvestigational

    It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C. … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia.

    Mixtures: MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 5 ADET, MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADETSynonyms: Neisseria meningitidis group C (strain C11) oligosaccharide CRM-197 adipic acid conjugate, Meningococcal group C polysaccharide
  3. Drug

    Chorionic Gonadotropin (Human)

    go.drugbank.com/drugs/DB09126
    ApprovedInvestigationalVet approved

    HCG is composed of an alpha and a beta sub-unit. … In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens.

    Synonyms: h-HCGProducts: MERIONAL® 75 UI, PROLUGYN1000 UI
  4. Drug

    Budesonide

    go.drugbank.com/drugs/DB01222
    ApprovedInvestigational

    [A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619] … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.

    Mixtures: BUDEK PLUS® 200/6 MCG, BUDEK PLUS® 200/6 MCGCategories: Agents to Treat Airway Disease, P-glycoprotein substrates
  5. Indication

    Pulmonary arterial hypertension WHO functional class I

    go.drugbank.com/conditions/DBCOND0160108
    Drugs: Ambrisentan · Selexipag · Sotatercept
    Synonyms: PAH WHO Group I, Pulmonary Arterial Hypertension WHO Group I
  6. Indication

    Relapsed Cutaneous T-cell Lymphoma Stage I

    go.drugbank.com/conditions/DBCOND0168685
    Drugs: Denileukin diftitox
    Synonyms: Relapsed Cutaneous T-cell Lymphoma Stage I
  7. Target

    HLA class I histocompatibility antigen, B alpha chain

    go.drugbank.com/bio_entities/BE0004082
    TargetHumans

    Antigen-presenting major histocompatibility complex class I (MHCI) molecule. … Can bind different peptides containing allele-specific binding motifs, which are mainly defined by anchor residues at position 2 and 9 (PubMed:25808313, PubMed:29531227).

    Polypeptides: HLA class I histocompatibility antigen, B alpha chainSynonyms: MHC class I antigen B*27, HLA class I histocompatibility antigen, B-27 alpha chain
  8. Drug

    Sodium fluorophosphate

    go.drugbank.com/drugs/DB09484
    ApprovedInvestigational

    Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

    Synonyms: Na MFPMixtures: K-MOM Kids Tooth, DOCTRUST K Tooth
  9. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.

    Mixtures: ALERMED® D, FEXU D® SUSPENSIONCategories: Histamine H1 Antagonists, Non-Sedating, P-glycoprotein substrates
  10. Target

    DNA-directed RNA polymerase I subunit RPA1

    go.drugbank.com/bio_entities/BE0012326
    TargetHumans

    Catalytic core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. … Forms Pol I active center together with the second largest subunit POLR1B/RPA2.

    Polypeptides: DNA-directed RNA polymerase I subunit RPA1Synonyms: RNA polymerase I subunit A1, RNA polymerase I 194 kDa subunit