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Displaying results 2891 - 2900 of 10000 in total
  1. Drug

    Asparagine

    go.drugbank.com/drugs/DB00174
    ApprovedNutraceuticalWithdrawn

    A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. … (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)

    Categories: Amino Acids, Peptides, and Proteins
  2. Drug

    Meningococcal polysaccharide vaccine group Y

    go.drugbank.com/drugs/DB13888
    ApprovedInvestigational

    Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup Y. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.

    Mixtures: Menveo Powder and Solution for Solution for Injection, NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
  3. Drug

    Imlifidase

    go.drugbank.com/drugs/DB15258
    ApprovedInvestigational

    [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior exposure to blood products, pregnancy, or any other circumstance which may have resulted in exposure … [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies.

    Categories: Antineoplastic and Immunomodulating Agents
  4. Drug

    Tovorafenib

    go.drugbank.com/drugs/DB15266
    ApprovedInvestigational

    [A263602] Tovorafenib inhibits BRAF and blocks dysregulated signalling pathways related to cancer cell growth and survival.[L50587] … [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation.

  5. Drug

    Vorasidenib

    go.drugbank.com/drugs/DB17097
    ApprovedInvestigational

    [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … [L51139] Vorasidenib displayed improved brain penetration and higher drug exposure compared to other IDH inhibitors such as [ivosidenib] and [enasidenib].

    Categories: Antineoplastic and Immunomodulating Agents
  6. Drug

    Calcium phosphate dihydrate

    go.drugbank.com/drugs/DB14481
    Approved

    Mixtures: NAVI Black and C-Clinic, Finefra Aid Tooth
  7. Target

    Cytohesin-2

    go.drugbank.com/bio_entities/BE0002654
    TargetHumans

    Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity).

    Synonyms: PH, SEC7 and coiled-coil domain-containing protein 2
  8. Drug

    Chikungunya vaccine (live, attenuated)

    go.drugbank.com/drugs/DB18701
    ApprovedInvestigational

    [L48726] It is approved for use in patients 18 years of age and older who are at high-risk of exposure to chikungunya virus. … Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia.

  9. Drug

    Cantharidin

    go.drugbank.com/drugs/DB12328
    ApprovedInvestigational

    [L47496] The approval was based on positive results from 2 phase III trials, CAMP-1 and CAMP-2, where 46% and 52% of patients treated with cantharidin achieved complete molluscum clearance, respectively … [A32892] Nevertheless, it gained its first FDA approval on Jul 21, 2023, under the brand name YCANTH™ by Verrica Pharmaceuticals for the treatment of molluscum contagiosum in adult and pediatric patients

  10. Drug

    Ribostamycin

    go.drugbank.com/drugs/DB03615
    ApprovedWithdrawn

    Ribostamycin is an aminoglycoside antibiotic[A187166] isolated from _Streptomyces ribosidificus_[A187178] listed as one of the World Health Organization's critically important antimicrobials.[L9071]