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Levobunolol Action Pathway
smpdb.ca/view/SMP0000666Drug actionLevobunolol (also known as Betagan) is an ophthalmic beta blocker (non-selective) that can produce cardiovascular effects and systemic pulmonary effects. Levobunolol bind to beta1-adrenergic and beta2-adrenergic receptors in heart and va...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Metipranolol Action Pathway
smpdb.ca/view/SMP0000667Drug actionMetipranolol (also known as Betanol or Disorat) is an beta blocker (non-selective) that can used as an antihypertensive, antiarrhythmic and antiglaucoma agent. Metipranolol binds to beta1-adrenergic and beta2-adrenergic receptors in hear...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Practolol Action Pathway
smpdb.ca/view/SMP0000669Drug actionPractolol (also known as Eraldin or Dalzic) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Practolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the bindin...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Nitrocefin
go.drugbank.com/drugs/DB11592ExperimentalNitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. … While other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingFormic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalIt is commonly used as a preservative and antibacterial agent in livestock feed.
Mixtures: Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA, V-NatalONT-093
go.drugbank.com/drugs/DB14069ExperimentalIn pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics. … ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp).
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingMethscopolamine
go.drugbank.com/drugs/DB11315ApprovedMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. … The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Mixtures: Dallergy PE, Allergy DN PEDutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalIt is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland.
Mixtures: DUTASTERIDE E TAMSULOSINA DOC, DUTASTERIDE E TAMSULOSINA DOCCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 SubstratesCobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalAlthough it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.
Mixtures: Prezcobix Ped, PREZCOBIX® TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceutical[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.
Synonyms: Co-enzyme Q 10, Coenzyme Q 10Mixtures: Q 10 Suprabio +L-Carnitine, Nova Q10+E softgel