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Trovafloxacin
go.drugbank.com/drugs/DB00685ApprovedWithdrawnIt was shown to be more effective against Gram-positive bacteria than Gram-negative bacteria when compared to previous fluoroquinolones. … It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Chenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalIt can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated. … It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones.
Products: CETEİX 250 MG SERT KAPSÜL, 100 ADET, KENDEO 250 MG SERT KAPSÜL, 100 ADETPlasminogen
go.drugbank.com/drugs/DB16701ApprovedInvestigational[L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions to form on the mucous membranes of patients, providing an unmet medical need for patients with
Alosetron
go.drugbank.com/drugs/DB00969ApprovedWithdrawnAlosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gas...
Pimethixene
go.drugbank.com/drugs/DB13292ApprovedIt is an anticholinergic used in the treatment of bronchitis.
Etilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnIt has been used as a vasoconstrictor agent.
International brands: Eti-PurenProducts: Effortil 7,5 mg/ml - Tropfen, ETILEFRINACLORHIDRATO 10 MG /MLXEN-2174
go.drugbank.com/drugs/DB05012ExperimentalNET is the primary mechanism regulating the biological effects of norepinephrine (NE) on the body. … XEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the Norepinephrine Transporter (NET).
Protriptyline
go.drugbank.com/drugs/DB00344ApprovedProtriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In...
Nialamide
go.drugbank.com/drugs/DB04820ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.