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Amylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnDespite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately [L1882]. … Although amylocaine could be administered topically or injected, it was most widely used for spinal anesthesia [L1882].
Contusugene ladenovec
go.drugbank.com/drugs/DB05322InvestigationalAdvexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents. … INGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials.
Umifenovir
go.drugbank.com/drugs/DB13609Investigational[A191475] It has been in use in Russia for approximately 25 years and in China since 2006. … [A191475] Umifenovir's ability to exert antiviral effects through multiple pathways has resulted in considerable investigation into its use for a variety of enveloped and non-enveloped RNA and DNA viruses
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSalicylamide
go.drugbank.com/drugs/DB08797ApprovedSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. … Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Alclometasone
go.drugbank.com/drugs/DB00240ApprovedAlclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
cryopreserved human liver cells
go.drugbank.com/drugs/DB05852ExperimentalVesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. … The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation
Tagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationala myeloid malignancy in the dendritic cell lineage. … [A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018 as the first FDA-approved treatment for blastic plasmacytoid dendritic cell neoplasm, which is
Oxyphencyclimine
go.drugbank.com/drugs/DB00383ApprovedOxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Categories: Drugs for Functional Gastrointestinal DisordersAripiprazole lauroxil
go.drugbank.com/drugs/DB14185ApprovedOn July 2nd, a different formulation of aripiprazole lauroxil marketed as Aristada Initio was FDA-approved for immediate initiation of Aristada at any dose. … Aripiprazole lauroxil was initially approved by the FDA in October 2015 under the market name Aristada for the treatment of schizophrenia.
Ingenol mebutate
go.drugbank.com/drugs/DB05013ApprovedWithdrawnPEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis.