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Leukotriene C4
go.drugbank.com/drugs/DB08855ExperimentalThe conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue.
Categories: SRS-ABrentuximab
go.drugbank.com/drugs/DB05471InvestigationalBrentuximab (SGN-30) is an engineered monoclonal antibody (mAb) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of hematologic malignancies as compared … SGN-30 has demonstrated objective antitumor responses as a single agent in phase II clinical trials.
Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalAn analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography. … It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.
Migalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigationalFabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). … unmet medical need and where a drug is shown to have certain effects that are reasonably likely to predict a clinical benefit to patients.
Categories: Alpha-Galactosidase A (alpha-Gal A) Pharmacological ChaperonesDifloxacin
go.drugbank.com/drugs/DB11511ExperimentalVet approvedDifloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. … However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Fuzapladib
go.drugbank.com/drugs/DB19478ExperimentalFuzapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Fuzapladib is a phospholipase A2 inhibitor. … Fuzapladib has a monoisotopic molecular weight of 379.12 Da.
Categories: Phospholipase A2 Inhibitors, Phospholipases A, antagonists & inhibitorsHydroxyethyl Starch
go.drugbank.com/drugs/DB09106ApprovedInvestigationalHES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
Categories: Compounds used in a research, industrial, or household settingSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalSorafenib is a bi-aryl urea and an oral multikinase inhibitor.
Categories: UGT1A9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexHesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: Cilobana Cpa TabInterferon alfa-n3
go.drugbank.com/drugs/DB00018ApprovedPurified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).