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Cysteine and glycine-rich protein 1
go.drugbank.com/bio_entities/BE0009098TargetHumansCould play a role in neuronal development
Polypeptides: Cysteine and glycine-rich protein 1Sodium- and chloride-dependent taurine transporter
go.drugbank.com/bio_entities/BE0009148TransporterHumansCan also mediate transport of beta-alanine, hypotaurine and gamma-aminobutyric acid (GABA) (PubMed:39837997, PubMed:40108165, PubMed:40789850, PubMed:41269860, PubMed:8010975) … Mediates sodium- and chloride-dependent transport of taurine, a key amino acid (PubMed:31345061, PubMed:31903486, PubMed:39837997, PubMed:40108165, PubMed:40108449, PubMed:40615403, PubMed:40789850, PubMed
Polypeptides: Sodium- and chloride-dependent taurine transporterTRAF2 and NCK-interacting protein kinase
go.drugbank.com/bio_entities/BE0009399TargetHumansMAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway (PubMed … Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development.
Polypeptides: TRAF2 and NCK-interacting protein kinaseAcid ceramidase
go.drugbank.com/bio_entities/BE0010906TargetHumansAlso catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine (PubMed:12764132, PubMed:12815059). … Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (PubMed:10610716, PubMed:11451951, PubMed:15655246, PubMed:26898341, PubMed:36752535, PubMed
Polypeptides: Acid ceramidaseSynonyms: Acid CDaseSodium- and chloride-dependent GABA transporter 1
go.drugbank.com/bio_entities/BE0000249TargetHumansMediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse (PubMed:30132828). … +), Cl(-) and GABA (By similarity).
Polypeptides: Sodium- and chloride-dependent GABA transporter 1Function: gamma-aminobutyric acid transmembrane transporter activitySodium- and chloride-dependent creatine transporter 1
go.drugbank.com/bio_entities/BE0000375TargetTransporterHumansPlays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity)
Polypeptides: Sodium- and chloride-dependent creatine transporter 1