Search

Displaying results 21 - 30 of 485 in total
  1. Target

    N-succinylamino acid racemase

    go.drugbank.com/bio_entities/BE0003211
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Catalyzes both N-succinylamino acid racemization and OSB synthesis at equivalent rates (PubMed:24872444). … , N-formyl-D-norleucine, N-carbamoyl-D-methionine and N-carbamoyl-D-norleucine (PubMed:15313614, PubMed:16650857, PubMed:25875730).

    Polypeptides: N-succinylamino acid racemaseSynonyms: N-acylamino acid racemase, o-succinylbenzoic acid synthase
  2. Target

    D-Amino acid amidase

    go.drugbank.com/bio_entities/BE0004262
    TargetOchrobactrum anthropi

    Polypeptides: D-Amino acid amidase
  3. Target

    Retinoic acid receptor gamma

    go.drugbank.com/bio_entities/BE0000144
    TargetHumans

    Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes … Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor gamma
  4. Target

    Aromatic-amino-acid aminotransferase

    go.drugbank.com/bio_entities/BE0001389
    TargetParacoccus denitrificans

    Shows activities toward both dicarboxylic and aromatic substrates.

    Polypeptides: Aromatic-amino-acid aminotransferase
  5. Target

    D-amino-acid oxidase

    go.drugbank.com/bio_entities/BE0004141
    TargetEnzymeHumans

    Required to catabolize D-amino acids synthesized endogenously, of gastrointestinal bacterial origin or obtained from the diet, and to use these as nutrients (By similarity). … Regulates the level of D-amino acid neurotransmitters in the brain, such as D-serine, a co-agonist of N-methyl D-aspartate (NMDA) receptors, and may modulate synaptic transmission (PubMed:17303072).

    Polypeptides: D-amino-acid oxidaseFunction: D-amino-acid dehydrogenase activity
  6. Target

    L-amino-acid oxidase

    go.drugbank.com/bio_entities/BE0004566
    TargetHumans

    Has preference for L-aromatic amino acids: converts phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp) to phenylpyruvic acid (PP), hydroxyphenylpyruvic acid (HPP), and indole-3-pyruvic acid (I3P) … IL4I1-mediated Trp catabolism generates I3P, giving rise to indole metabolites (indole-3-acetic acid (IAA) and indole-3-aldehyde (I3A)) and kynurenic acid, which act as ligands for AHR, a ligand-activated

    Polypeptides: L-amino-acid oxidaseFunction: L-amino-acid oxidase activity
  7. Target

    Lysophosphatidic acid receptor 1

    go.drugbank.com/bio_entities/BE0017535
    TargetHumans

    Receptor for lysophosphatidic acid (LPA) (PubMed:19306925, PubMed:25025571, PubMed:26091040, PubMed:9070858). … Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus. Plays a role in pain perception and in the initiation of neuropathic pain (By similarity)

    Polypeptides: Lysophosphatidic acid receptor 1Synonyms: Lysophosphatidic acid receptor Edg-2
  8. Target

    Delta-aminolevulinic acid dehydratase

    go.drugbank.com/bio_entities/BE0000050
    TargetEnzymeHumans

    Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen

    Polypeptides: Delta-aminolevulinic acid dehydratase
  9. Target

    Cysteine sulfinic acid decarboxylase

    go.drugbank.com/bio_entities/BE0000079
    TargetHumans

    Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. … Does not exhibit any decarboxylation activity toward glutamate

    Polypeptides: Cysteine sulfinic acid decarboxylase
  10. Target

    Hydroxycarboxylic acid receptor 2

    go.drugbank.com/bio_entities/BE0000635
    TargetHumans

    Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis … Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated

    Polypeptides: Hydroxycarboxylic acid receptor 2Synonyms: Nicotinic acid receptor