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Displaying results 291 - 300 of 7452 in total
  1. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for some sexually transmitted and enteric infections. … The results were positive, all patients taking the combination were virologically cured within 6 days of treatment, however, larger studies are required.[A192546]

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Zithrolide 500mg Powder for Solution for Infusion, Azithromycin powder for solution for injection 500mg
  2. Drug

    Brentuximab vedotin

    go.drugbank.com/drugs/DB08870
    ApprovedInvestigational

    This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739] … Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously untreated stage III or IV classical Hodgkin lymphoma (cHL) in combination with chemotherapy.

    Products: ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION), POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL
  3. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for … the convenience of daily or twice-daily dosing.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: CYROSEF POWDER FOR SOLUTION FOR INJECTION 2GM, CYROSEF POWDER FOR SOLUTION FOR INJECTION 1GM
  4. Drug

    Idarucizumab

    go.drugbank.com/drugs/DB09264
    Approved

    Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations. … anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease, concomitant NSAID or

    Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/ML
  5. Drug

    Necitumumab

    go.drugbank.com/drugs/DB09559
    ApprovedInvestigationalWithdrawn

    Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC).

    Products: PORTRAZZA CONCENTRATE FOR SOLUTION FOR INFUSION 800MG/50ML
  6. Drug

    Isavuconazonium

    go.drugbank.com/drugs/DB06636
    ApprovedInvestigational

    This formulation also avoids the use of a cyclodextrin vehicle for solubilization required for intravenous administration of other antifungals such as voriconazole and posaconazole, eliminating concerns … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and parenteral formulations.

    Products: CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MG
  7. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: SOFICLOR FOR ORAL SUSPENSION 125 mg/5 ml, VERCEF GRANULES FOR RECONSTITUTION 187 mg/5 ml
  8. Drug

    Degarelix

    go.drugbank.com/drugs/DB06699
    ApprovedInvestigational

    Degarelix is used for the treatment of advanced prostate cancer.

    Products: Firmagon 120mg Powder and Solvent for Solution for Injection, Firmagon 80mg Powder and Solvent for Solution for Injection
  9. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is a...

    Products: Bivalirudin for Injection, Bivalirudin Accord 250 mg Pulver für ein Konzentrat zur Herstellung einer Injektions-/Infusionslösung
  10. Drug

    Ixekizumab

    go.drugbank.com/drugs/DB11569
    ApprovedInvestigational

    It is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. … Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing.

    Products: Taltz 80mg solution for injection in pre-filled pen, TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml