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Rotavirus vaccine
go.drugbank.com/drugs/DB10276ApprovedInvestigationalRotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.[L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. … [Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.[L1117]
Salts: Human Rotavirus A type G1P7(5) strain WI79 live antigen, Human Rotavirus A type G2P7(5) strain SC2 live antigenMixtures: ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS, ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUSCefoperazone
go.drugbank.com/drugs/DB01329ApprovedInvestigationalWithdrawnWhile its clinical use has been discontinued in the U.S., cefoperazone is available in several European countries most commonly under the product name, Sulperazon. … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis
Mixtures: PRİMASEF 500 MG IM/IV ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET, PRİMASEF 1000 MG IM/IV ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Mixtures: L-OMBRIX-DUET, L-OMBRIX-DUETCategories: Heterocyclic Compounds, 2-RingAldafermin
go.drugbank.com/drugs/DB16086InvestigationalStudy in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)). … Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center
Synonyms: (phe5>met,ser6>arg,ala8>ser,gly9>ser,his11>leu) fibroblast growth factor 19 (human fgf19) (5-194)-peptide, produced in escherichia coliTicagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigational[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. … Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolAllantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].
Mixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 GCategories: Heterocyclic Compounds, 1-RingDidanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olOxacillin
go.drugbank.com/drugs/DB00713ApprovedInvestigationalAn antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (5-methyl-3-phenyl-4-isoxazolyl)penicillin, 5-methyl-3-phenyl-4-isoxazolyl-penicillinTedizolid phosphate
go.drugbank.com/drugs/DB09042ApprovedThis product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved [linezolid] and is generally effective against multidrug-resistant Gram-positive
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingSynonyms: [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphateIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigationalIoversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. … [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivitySynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide