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Doxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigational[T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … [T83] In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: DOXEPIN AL 50, DOXEPIN AL 100Diclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).
Mixtures: TAFIROL ACCategories: P-glycoprotein inducers, Cytochrome P-450 SubstratesPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: IV Infusion CPIProducts: PRESTIGE® PRILOCAINA CLORHIDRATO AL 4%Pancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Products: KREON 35000 PH EUR LIP EI, Pancrex V PowderTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigational[A4269,A183842] Tramadol has also been shown to affect a number of other pain modulators within the central nervous system as well as non-neuronal inflammatory markers and immune mediators. … of pain types including neuropathic pain, post-operative pain, lower back pain, as well as pain associated with labour, osteoarthritis, fibromyalgia, and cancer.
Mixtures: Ag-acet-tramadol, DUODUET - PTCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalfor an extended period. … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OXYCODON HCL AL 15MG, OXYCODON HCL AL 5MG RETPrasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalAs a result, inhibition of ADP-mediated platelet activation and aggregation occurs. … Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: PRASUGREL AL 5MG HBR FTA, PRASUGREL AL 10MG HBR FTACarboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalIt is added in food products as a viscosity modifier or thickener and emulsifier. … The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface [A33029]. Sodium carboxymethylcellulose is the most commonly used salt.
Mixtures: Refresh Digital PF, Refresh RELIEVA PFCategories: Compounds used in a research, industrial, or household settingCalcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalBone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. … The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions.
Mixtures: T-PA Cap, Fusion PM Formula TabProducts: Ag-X, ENA Actimineral A