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Trihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.
Categories: Heterocyclic Compounds, 1-RingProducts: POZHEXOL 5, ACA (5 mg.)Mexiletine
go.drugbank.com/drugs/DB00379ApprovedInvestigationalAntiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Synonyms: 1-(2',6'-dimethylphenoxy)-2-aminopropane, (±)-1-(2,6-dimethylphenoxy)propan-2-amineCategories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than
Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Amlodipine 5, Amlodipin-Mepha 5/10Procyclidine
go.drugbank.com/drugs/DB00387ApprovedInvestigationalA muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride, 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanolRemoxipride
go.drugbank.com/drugs/DB00409ApprovedWithdrawnRemoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsRosiglitazone
go.drugbank.com/drugs/DB00412ApprovedInvestigationalThis is the subject of a clinical trial currently underway. … Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: (±)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione, (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedionAmpicillin
go.drugbank.com/drugs/DB00415ApprovedInvestigationalVet approvedAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Mixtures: DEVASİD 1 G/0,5 G I.M. ENJEKSİYONLUK TOZ, 1 FLAKON, DUOBAK 2 G/1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETCategories: Penicillin G, Heterocyclic Compounds, 2-RingCyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine, 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidineEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine … Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Categories: Hepatitis B virus, Cytochrome P-450 SubstratesProducts: KALVIR® 1 MG, Tecavir 1 (Entecavir Tablets 1 mg)Epirubicin
go.drugbank.com/drugs/DB00445ApprovedInvestigationalAn anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Categories: UGT2B7 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSIDE, 4'-Epiadriamycin