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Tolazamide
go.drugbank.com/drugs/DB00839ApprovedA sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismSynonyms: N-(p-Toluenesulfonyl)-N'-hexamethyleniminoureaClotiazepam
go.drugbank.com/drugs/DB01559ApprovedIllicitClotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.
Categories: Benzodiazepines and benzodiazepine derivativesInflammatory Muscle Disease
go.drugbank.com/conditions/DBCOND0155571Synonyms: Other inflammatory and immune myopathies, not elsewhere classifiedOsteoarthritis of the Knee
go.drugbank.com/conditions/DBCOND0032623Synonyms: Osteoarthritis and allied disorders, Osteoarthritis in the KneeViomycin
go.drugbank.com/drugs/DB06827ApprovedThese drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete _Streptomyces puniceus_. … Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin.
Categories: Amino Acids, Peptides, and ProteinsAlosetron
go.drugbank.com/drugs/DB00969ApprovedWithdrawnAlosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes.
Categories: Alimentary Tract and MetabolismPlasminogen
go.drugbank.com/drugs/DB16701ApprovedInvestigational[L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions to form on the mucous membranes of patients, providing an unmet medical need for patients with … [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh)[L34620] for the treatment of type 1 plasminogen deficiency (hypoplasminogenemia).
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsAnsuvimab
go.drugbank.com/drugs/DB16385ApprovedInfection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as … [A207646] Ansuvimab received FDA approval on December 21, 2020, and is currently marketed as Ebanga by Ridgeback Biotherapeutics, LP. Ansuvimab is just the second FDA-approved treatment for EVD.
Categories: Amino Acids, Peptides, and Proteins, Immune Sera and ImmunoglobulinsBempedoic acid
go.drugbank.com/drugs/DB11936ApprovedInvestigationalCaused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. … [L12144,L12147] It was developed by Esperion Therapeutics Inc. and approved by the FDA on February 21, 2020.
Categories: bempedoic acid and ezetimibeFredrickson Type III lipidemia
go.drugbank.com/conditions/DBCOND0106234Drugs: AtorvastatinSynonyms: Familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia, Familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemia