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Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIn some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological or surgical intervention is required. … [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ORALLI LW®, SLENDER 1Amoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Mixtures: BIOMICILINA®POLVO PARA RECONSTITUIR A 100ML DE SUSPENSION ORAL, AMOXICILINA + CLAVULANATO DE POTASIO 400 + 57 MG / 5 ML POLVO PARA RECONSTIUTIR A SUSPENSIÓN ORALCategories: Penicillin G, Heterocyclic Compounds, 1-RingTerfenadine
go.drugbank.com/drugs/DB00342ApprovedWithdrawnIn the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-olDequalinium
go.drugbank.com/drugs/DB04209Approved[A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. … Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems.
Mixtures: DEQ LOZENGE, DEQ LOZENGECategories: Heterocyclic Compounds, 2-RingTetryzoline
go.drugbank.com/drugs/DB06764ApprovedTetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. … [A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant.
Mixtures: ISCHEMOL A, ISCHEMOL ACategories: Compounds used in a research, industrial, or household setting, Sympathomimetics Used as DecongestantsL-lactate dehydrogenase A-like 6A
go.drugbank.com/bio_entities/BE0000297TargetHumansCatalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme (PubMed:18351441).
Polypeptides: L-lactate dehydrogenase A-like 6AD-alanine--D-alanine ligase A
go.drugbank.com/bio_entities/BE0000733TargetEscherichia coli (strain K12)Cell wall formation.
Polypeptides: D-alanine--D-alanine ligase ASynonyms: D-Ala-D-Ala ligase A, D-alanylalanine synthetase APeptidyl-prolyl cis-trans isomerase A
go.drugbank.com/bio_entities/BE0001014TargetHumansInhibits replication of influenza A virus (IAV) (PubMed:19207730). … Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (PubMed:11943775
Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase ARibosomal small subunit pseudouridine synthase A
go.drugbank.com/bio_entities/BE0001276TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase AMethane monooxygenase component A alpha chain
go.drugbank.com/bio_entities/BE0003331TargetEnzymeMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
Polypeptides: Methane monooxygenase component A alpha chain