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Phenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Synonyms: (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol, l-(3-Hydroxyphenyl)-N-methylethanolamineMixtures: CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML, PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 MLFosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalFosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 AntagonistsProducts: BRIAN EX, APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationaland other fatty substances in the blood). … Like other protease inhibitors, it is used only in combination with other HIV medications. The U.S. Food and Drug Administration (FDA) approved atazanavir on June 20, 2003.
Mixtures: ANCEF ® R, ANCEF ® RCategories: Antivirals used in combination for the treatment of HIV infections, P-glycoprotein inducersDimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigationalIt is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … in response to oxidative stress.
Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: DIMETILFUMARATO EG, YARDIX® 120 MGBesifloxacin
go.drugbank.com/drugs/DB06771ApprovedBesifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Categories: 4-Quinolones, Heterocyclic Compounds, 1-RingProducts: BESIVANCE % 0,6 OFTALMIK SÜSPANSIYON, 5 MLTriazolam
go.drugbank.com/drugs/DB00897ApprovedInvestigationalInternationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances. … Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: SOMESE® 0.25 MG TABLETAS, TRIAZOLAM EGHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444] … [A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.
Mixtures: VASDAY 5 MG/5 MG/25 MG FİLM KAPLI TABLET (90 ADET), VASDAY 5 MG/5 MG/25 MG FİLM KAPLI TABLET (30 ADET)Categories: Heterocyclic Compounds, 2-RingProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1
go.drugbank.com/bio_entities/BE0000087TargetHumansPart of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine r...
Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1Gamma-aminobutyric acid receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0000471TargetHumansExtrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … GABAARs containing alpha-5/GABRA5 subunits are mainly extrasynaptic and contribute to the tonic GABAergic inhibition in the hippocampus (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABAAR subunit alpha-5, GABA(A) receptor subunit alpha-51-deoxy-D-xylulose 5-phosphate reductoisomerase
go.drugbank.com/bio_entities/BE0001575TargetEscherichia coli (strain K12)Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 1-deoxy-D-xylulose 5-phosphate reductoisomeraseSynonyms: 1-deoxyxylulose-5-phosphate reductoisomerase