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Aclerastide
go.drugbank.com/drugs/DB12631InvestigationalAclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Synonyms: 1-7-ANGIOTENSIN II, 3-L-NORLEUCINE-5-L-ISOLEUCINE, NorLeu3-Angiotensin(1-7) [NorLeu3-A(1-7)]Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved … the use of baricitinib for the treatment of COVID-19 in May 2022.
Categories: Heterocyclic Compounds, 1-Ring, MATE 2 InhibitorsProducts: UNAMİTY 2 MG FİLM KAPLI TABLET, 14 ADET, UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADETDYN-101
go.drugbank.com/drugs/DB17921InvestigationalDYN-101 is an antisense product candidate designed to reduce the expression of dynamin 2 protein.
Synonyms: 5’-cEtG-sp-cEt5MeU-sp-cEt5MeU-sp-dT-sp-dA-sp-dT-sp-dT-spdA-sp-dT-sp-dA-sp-dG-sp-dG-sp-dG-sp-cEt5MeC-sp-cEt5MeU-sp-cEt5MeU-3’, DYN 101Agomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalAgomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. … It is currently sold in Australia under the Valdoxan trade name.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsProducts: VALDOXAN 25 MG, VALDOXAN® 25 MGSelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalMost recently, on November 20, 2025, the FDA expanded this indication to include adults [L53881] … [A193611] "The novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform
Categories: Mitogen-Activated Protein Kinase Kinase 1 Inhibitors, Heterocyclic Compounds, 2-RingProducts: Koselugo Hard Capsules 10 mg, Koselugo Hard Capsules 25 mgBatoprotafib
go.drugbank.com/drugs/DB19137InvestigationalBatoprotafib is under investigation in clinical trial NCT04330664 (Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)).
Synonyms: (3s,4s)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl)sulfanyl)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro(4.5)decan-4-aminePerazine
go.drugbank.com/drugs/DB12710ApprovedWithdrawnPerazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Categories: Heterocyclic Compounds, 3-RingProducts: PERAZIN-NEURAX 25 MG, PERAZIN-NEURAX 100 MGTilmicosin
go.drugbank.com/drugs/DB11471InvestigationalVet approvedTilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with _Mannheimia haemolytica_.
Categories: P-glycoprotein substratesProducts: EM-MICOFEED 10% Granules, TILMICOSIN 100 mg/ml Oral SolutionMedronic acid
go.drugbank.com/drugs/DB14078ApprovedInvestigationalProducts: MON MDP KIT 10 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET, DRAXIMAGE® MDPOpium
go.drugbank.com/drugs/DB11130ApprovedIllicitIt has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. … During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive.[A32171] Opium is extracted from _Papaver somniferum_, which is more known as poppies.
Mixtures: Donnagel-PG Liq, Donnagel-PG CapCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates