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Ergoloid mesylate
go.drugbank.com/drugs/DB01049Approved[A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued.
Trabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalOn October 23, 2015, the FDA approved trabectedin, (as Yondelis), for the treatment of specific soft tissue sarcomas.
Technetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnHowever disofenin is the most commonly used iminodiacetic acid since it has a high liver to renal extraction and its hepatic uptake is not as highly dependent on serum bilirubin levels (a competitive inhibitor
Abemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalOn September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for the treatment of HR-positive and HER2-negative advanced or metastatic breast cancer that has progressed
Paliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.
Varespladib methyl
go.drugbank.com/drugs/DB05737InvestigationalStudies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.
Neocartilage
go.drugbank.com/drugs/DB05257InvestigationalNeocartilage is the only scaffold-free living cartilage graft on the market.
Trelagliptin
go.drugbank.com/drugs/DB15323InvestigationalTrelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
Adenosine 5'-phosphosulfate
go.drugbank.com/drugs/DB03708InvestigationalThe initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.
Seltorexant
go.drugbank.com/drugs/DB14961InvestigationalSeltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).