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Lutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalIn terms of biodistribution, Lutetium Lu 177 dotatate demonstrated a lower whole-body retention, indicating potentially lower risk for bone marrow toxicity [A31696]. … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with
Categories: Compounds used in a research, industrial, or household settingSynonyms: Lutetium Lu 177 DOTA(0)-Tyr(3)-Octreotate, 177-Lu DOTA-0-Tyr3-OctreotateZalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnA dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. … The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one, 2',3'-DideoxycytidineDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Mixtures: DESLAIR® - D, DESLODEX ® D CÁPSULASCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingSelenium Sulfide
go.drugbank.com/drugs/DB00971ApprovedSelenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent … Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea.
Products: Selsun Blue 2-in-1, Selsun Blue, 2-IN-1Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalEzetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. … C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids.
Mixtures: TIAZOMET S®, TIAZOMET S®Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2C8 InhibitorsTelithromycin
go.drugbank.com/drugs/DB00976ApprovedTelithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: KETEK ® 400 MGRamelteon
go.drugbank.com/drugs/DB00980ApprovedInvestigationalRamelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: RAMELDA 8 MG FILM KAPLI TABLET,30 ADET, ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADETIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigationalIsotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Mixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNandrolone phenpropionate
go.drugbank.com/drugs/DB00984ApprovedIllicitIt is a schedule III drug in the U.S.
Auranofin
go.drugbank.com/drugs/DB00995ApprovedInvestigationalIt has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. … Heme oxygenase 1 is an inducible heme-degrading enzyme with anti-inflammatory properties.
Synonyms: 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold, (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate