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Displaying results 3051 - 3060 of 10000 in total
  1. Drug

    Natalizumab

    go.drugbank.com/drugs/DB00108
    ApprovedInvestigational

    Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMER, IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMER
  2. Drug

    Prednisolone hemisuccinate

    go.drugbank.com/drugs/DB14633
    Investigational

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists, Cytochrome P-450 CYP3A InducersProducts: Prednisolut 50 mg Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung, Solu - Dacortin 50 mg - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung oder Infusionslösung
  3. Drug

    Benperidol

    go.drugbank.com/drugs/DB12867
    ApprovedWithdrawn

    Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

    Products: BENPERIDOL-NEURAX 10 MG, BENPERIDOL-NEURAX 2 MG
  4. Drug

    Hydroxyethyl Starch

    go.drugbank.com/drugs/DB09106
    ApprovedInvestigational

    HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.

    Mixtures: Tetraspan Solution for Infusion 10%, Tetraspan 10% Solution for InfusionCategories: Compounds used in a research, industrial, or household setting, Blood and Related Products
  5. Drug

    Plerixafor

    go.drugbank.com/drugs/DB06809
    ApprovedInvestigational

    [A7117] Compared to placebo with G-CSF, the plerixafor and G-CSF mobilization regimen has a higher probability of achieving the optimal CD34+ cell target for tandem transplantation in fewer apheresis procedures … [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved by the US Food and Drug Administration on December 15, 2008.[A7117,L45678]

    Categories: Antineoplastic and Immunomodulating AgentsProducts: MOZOBIL 20 MG/ ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET, Mozofor 24 mg/1,2 mL S.C. Enjeksiyonluk Çözelti, 1 ADET
  6. Drug

    Ferrous sulfate anhydrous

    go.drugbank.com/drugs/DB13257
    ApprovedInvestigational

    Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. … [A190528] Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency. It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246]

    Mixtures: Exact-Rx SODIUM SULFACETAMIDE and SULFER 10%/5% Cleanser, Ferrograd - Fol 105 mg / 0,35 mg FilmtablettenSynonyms: iron sulfate (1:1), iron(2+) sulfate (anhydrous)
  7. Drug

    Padimate O

    go.drugbank.com/drugs/DB11570
    Approved

    Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic effects on yeast i_n vivo_ [A32458].

    Synonyms: Padimate O, Padimate-OMixtures: Kiss My Face Everyday Moisturizer SPF 15-lot, Kiss My Face SPF 18 Lip Balm
  8. Drug

    Manganese gluconate

    go.drugbank.com/drugs/DB11141
    Approved

    It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. … Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O.

    Mixtures: Cal-mag Plus K, Mn and Zn Caplets, Vital Be-100Synonyms: Manganese D-gluconate
  9. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … However, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but

    Synonyms: FSH-a, FSH-bInternational brands: Cinnal-F
  10. Drug

    Glimepiride

    go.drugbank.com/drugs/DB00222
    ApprovedInvestigational

    Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular … [A177703] It is effective in reducing fasting plasma glucose, postprandial glucose, and glycosylated hemoglobin levels and is considered to be a useful, cost-effective treatment option for managing type

    Mixtures: AMARYL®M 1 MG/ 500 MG, DUERID 30/2 MG TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates