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Displaying results 301 - 310 of 10000 in total
  1. Drug

    Meperidine

    go.drugbank.com/drugs/DB00454
    ApprovedInvestigational

    A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...

    Products: DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml, Demerol 10%-liq Im IV Sc
  2. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.

    Mixtures: Cellmov Cell Line Mask, Jayjun Honey Dew Red MaskSynonyms: beta-D-Adenosine, 9-beta-D-Ribofuranosidoadenine
  3. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Mixtures: UNASYN IM/IV 1.5G, UNASYN IM/IV 0.75GSynonyms: D-(−)-ampicillin, D-(−)-6-(α-aminophenylacetamido)penicillanic acid
  4. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals

    Mixtures: FOSINOPRIL E IDROCLOROTIAZIDE DOC GENERICI, FOSINOPRIL E IDROCLOROTIAZIDE DOC GENERICICategories: Agents Acting on the Renin-Angiotensin System
  5. Pathway

    The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria

    smpdb.ca/view/SMP0002358
    Disease

    This results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation. … L-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.

    Drugs: Pyruvic acid · Biotin · L-Glutamine · Succinic acid · Glutamic acid · NADH +6 more
  6. Drug

    Methylprednisolone hemisuccinate

    go.drugbank.com/drugs/DB14644
    ApprovedInvestigational

    A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

    Categories: Compounds used in a research, industrial, or household settingProducts: SOLU-MEDROL DE 40 MG SOLUCION, METICURE 20 MG IM/IV ENJEKSIYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET
  7. Drug

    Lamotrigine

    go.drugbank.com/drugs/DB00555
    ApprovedInvestigational

    Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries. … Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder.

    Products: Lamotrigin Genericon 25 mg lösliche Tabletten, Lamotrigin Genericon 50 mg lösliche Tabletten
  8. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

    Synonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneProducts: PALONOSETRON DR. REDDY'S, PALONEX 250MCG/5ML IV ENJEKSIYONLUK ÇÖZELTI, 1 ADET
  9. Drug

    Mycophenolate mofetil

    go.drugbank.com/drugs/DB00688
    ApprovedInvestigational

    [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. … [A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases.

    Products: MICOFENOLATO MOFETILE DOC GENERICI, MICOFENOLATO MOFETILE MYLAN GENERICS
  10. Drug

    Tolcapone

    go.drugbank.com/drugs/DB00323
    ApprovedInvestigationalWithdrawn

    Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. … It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.

    International brands: Sen De NingProducts: TASMAR ROCHE TABLETAS LACADAS DE 200 MG, TASMAR ROCHE TABLETA LACADA DE 100 MG