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Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017. … [L7186,L7192,L41439] Dupilumab is currently under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, and
Categories: Agents for Dermatitis, Excluding CorticosteroidsProducts: Dupixent 300 mg Solution for Injection in Pre-filled Syringe, Dupixent 200mg Solution for Injection in Pre-Filled SyringeNicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalIt has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Categories: Antihypertensive Agents Indicated for HypertensionProducts: Nicardiin 1mg/ml Solution for Infusion, Nicardipine Hydrochloride in Sodium ChlorideCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
Mixtures: Arthricare for Women Multi-action, Fors Pain ReliefCategories: Topical Products for Joint and Muscular Pain, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesIxekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIt is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions.
Products: Taltz 80mg solution for injection in pre-filled pen, TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/mlDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957. … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Mixtures: Benylin for Children All-IN-one Cold & Fever, Cough-en RX LinctusCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Heterocyclic Compounds with 4 or More RingsPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalWhile its use has been approved in the early 1960's by the FDA [A32163], safety and effectiveness of pyrithione zinc has been reported for decades. … It is not shown to have any significant estrogenic activity according to the _in vivo_ and _in vitro_ assays [A32163].
Mixtures: Seaseal Bamboo Salt Mineral Anti Hair Loss, ReEn Mogangbichaek for Sensitive ScalpSynonyms: Pyridinethiol N-oxideIohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivitySynonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideLanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalIt is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. … Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome
Products: Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg, Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mgRacementhol
go.drugbank.com/drugs/DB14123ApprovedInvestigationalMixtures: Provault Muscle Salve, Icy Hot No Mess Vapor Cough Suppresant for KidsProducts: Imada Four Seasons Safe Analgesic Balm, Tieso for Man Male CleanserDacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalDacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma. … An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564).
Products: Dacarbazine for Injection BP, Dacarbazine for Injection