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XL784
go.drugbank.com/drugs/DB04991InvestigationalXL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation.
Darolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigationalDarolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBromfenac
go.drugbank.com/drugs/DB00963ApprovedWithdrawnNon-ophthalmic formulations of bromfenac were withdrawn in the US in 1998 due to cases of severe liver toxicity.[L43942,T239] … Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation.
Calcium cation
go.drugbank.com/drugs/DB14577InvestigationalMixtures: POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 150 ML (PVC TORBA) SETLI, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 150 ML (PVC TORBA) SETSİZDexamethasone acetate
go.drugbank.com/drugs/DB14649ApprovedInvestigationalVet approvedDexamethasone was therefore recommended as a life-saving treatment for COVID-19 patients experiencing severe respiratory symptoms.[L14318] … Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.
Mixtures: DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML, DUODECADRON ® SUSPENSIÓN INYECTABLE 1 MLCategories: Cytochrome P-450 CYP2A6 Inducers, Cytochrome P-450 SubstratesPotassium sulfate
go.drugbank.com/drugs/DB14499ApprovedSynonyms: Potassium (as sulfate)Mixtures: VINATAL DHA CAPSULA DE GELATINA BLANDABismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnBismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic … The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Ospemifene
go.drugbank.com/drugs/DB04938ApprovedOspemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesLevopropoxyphene
go.drugbank.com/drugs/DB06793ApprovedWithdrawnLevopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. … This drug presented different dosages and it was administered as a capsule or suspension.
De Novo Triacylglycerol Biosynthesis TG(15:0/18:1(11Z)/18:4(6Z,9Z,12Z,15Z))
smpdb.ca/view/SMP0017174MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...