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Cisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalCisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-Pentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnPentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160].
Mixtures: GAYABEN 150 ML SURUP, V-cofProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Categories: Compounds used in a research, industrial, or household settingSynonyms: Coenzym M, Coenzima MDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
go.drugbank.com/bio_entities/BE0003558TargetHumansCatalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (PubMed:10725373, PubMed:10906126, PubMed:11050148)
Polypeptides: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activityTechnetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalThis is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted … Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-.
Mixtures: TECHNELITE® GENERADOR DE TECNECIO TC 99M, POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSCategories: Compounds used in a research, industrial, or household settingNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
go.drugbank.com/bio_entities/BE0000243TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...
Polypeptides: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial5'-AMP-activated protein kinase catalytic subunit alpha-1
go.drugbank.com/bio_entities/BE0000677TargetHumansCatalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...
Polypeptides: 5'-AMP-activated protein kinase catalytic subunit alpha-1tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase
go.drugbank.com/bio_entities/BE0002518TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
Polypeptides: tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferaseHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
go.drugbank.com/bio_entities/BE0003134TargetHumansSpecifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity...
Polypeptides: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AFunction: 3',5'-cyclic-AMP phosphodiesterase activityLeucine-rich repeat-containing G protein-coupled receptor 5
go.drugbank.com/bio_entities/BE0010835TargetHumansReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with ph...
Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5